Publications

Researches

Association of Clinicopathologic and Molecular Tumor Features With Recurrence in Resected Early-Stage Epidermal Growth Factor Receptor-Positive Non-Small Cell Lung Cancer

Published Date: 5-Nov-2021
Name of Corresponding Authors and Institutions: Tan DSW, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: JAMA Network Open

Publication DOI: doi:10.1001/jamanetworkopen.2021.31892

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Stephanie P L Saw, Siqin Zhou, Jianbin Chen, Gillianne Lai, Mei-Kim Ang, Kevin Chua, Ravindran Kanesvaran, Quan Sing Ng, Amit Jain, Wan Ling Tan, Tanujaa Rajasekaran, Darren W T Lim, Aaron Tan, Kam Weng Fong, Angela Takano, Xin Ming Cheng, Kiat Hon Lim, Tina Koh, Boon-Hean Ong, Eng Huat Tan, Chee Keong Toh, Anders J Skanderup, Sze Huey Tan, Daniel S W Tan

Link to article in Journal: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785908

Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures

Published Date: 1-Sep-2021
Name of Corresponding Authors and Institutions: N. Gopalakrishna Iyer (NCCS)

Name of Journal, Conference Books or Other Publications: Cancer Immunology, Immunotherapy

Publication DOI: doi: 10.1007/s00262-021-03047-7

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Yvonne H. F. Teng, Hong Sheng Quah, Lisda Suteja, João M. L. Dias, Annalisa Mupo, Rachael J. M. Bashford-Rogers, George S. Vassiliou, Melvin L. K. Chua, Daniel S. W. Tan, Darren W. T. Lim & N. Gopalakrishna Iyer

Link to article in Journal: https://rdcu.be/cCGzA

Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities

Published Date: 14-Jul-2021
Name of Corresponding Authors and Institutions: Anders J Skanderup/GIS; Tan DSW, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Clinical Cancer Research

Publication DOI: https://doi.org/10.1158/1078-0432.CCR-20-4607

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Khi Pin Chua, Yvonne H.F. Teng, Aaron C. Tan, Angela Takano, Jacob J.S. Alvarez, Rahul Nahar, Neha Rohatgi, Gillianne G.Y. Lai, Zaw Win Aung, Joe P.S. Yeong, Kiat Hon Lim, Marjan Mojtabavi Naeini, Irfahan Kassam, Amit Jain, Wan Ling Tan, Apoorva Gogna, Chow Wei Too, Ravindran Kanesvaran, Quan Sing Ng, Mei Kim Ang, Tanujaa Rajasekaran, Devanand Anantham, Ghee Chee Phua, Bien Soo Tan, Yin Yeng Lee, Lanying Wang, Audrey S.M. Teo, Alexis Jiaying Khng, Ming Jie Lim, Lisda Suteja, Chee Keong Toh, Wan-Teck Lim, N. Gopalakrishna Iyer, Wai Leong Tam, Eng-Huat Tan, Weiwei Zhai, Axel M. Hillmer, Anders J. Skanderup and Daniel S.W. Tan

Link to article in Journal: https://clincancerres.aacrjournals.org/content/27/21/5939

Individualized Molecular Profiling for Allocation “to Clinical Trials Singapore Study—An Asian Tertiary Cancer Center Experience

Published Date: 18-May-2021
Name of Corresponding Authors and Institutions: Dr Daniel Tan, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: JCO Precision Oncology

Publication DOI: https://doi.org/10.1200/PO.20.00261

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Amanda O. L. Seet (NCCS), Aaron C. Tan (NCCS), Tira J. Tan (NCCS), Matthew C. H. Ng (NCCS), David W. M. Tai (NCCS), Justina Y. C. Lam (NCCS), Gek San Tan (SGH), Apoorva Gogna (SGH), Chow Wei Too (SGH), Bien Soo Tan (SGH), Angela Takano (SGH), Alvin Lim (SGH), Tse Hui Lim (SGH), Soon Thye Lim (NCCS), Rebecca Alexandra Dent (NCCS), Mei Kim Ang (NCCS), Yoon-Sim Yap (NCCS), Iain B. H. Tan (NCCS), Su Pin Choo (NCCS), Chee Keong Toh (NCCS), Elaine H. Lim (NCCS), Mohamad Farid (NCCS), Anders Jacobsen Skanderup (GIS), N. Gopalakrishna Iyer (NCCS), Wan Teck Lim (NCCS), Eng Huat Tan (NCCS), Tony K. H. Lim (SGH), and Daniel S. W. Tan (NCCS)

Intra-tumoral CD39+CD8+ T cells predict response to PD-1/PD-L1 blockade in patients with NSCLC

Published Date: 08-May-2021
Name of Corresponding Authors and Institutions: Dr Daniel Tan, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Journal of Thoracic Oncology

Publication DOI: https://doi.org/10.1016/j.jtho.2021.04.016

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Joe Yeong (SGH, IMCB), Lisda Suteja (NCCS), Yannick Simoni (SIGN), Kah Weng Lau (SGH, IMCB), Aaron C. Tan (NCCS), Hui Hua Li (SGH), Sherlly Lim (SGH), Jie Hua Loh (SGH), Felicia Wee Yu Ting (SGH), Sanjna Nilesh Nerurkar (NUS), Angela Takano (SGH), Eng Huat Tan (NCCS), Tony Kiat Hon Lim (SGH), Evan W. Newell (SIGN), Daniel S.W. Tan (NCCS)

Link to article in Journal: https://www.jto.org/article/S1556-0864(21)02155-9/fulltext

Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

Published Date: 13-Apr-2021
Name of Corresponding Authors and Institutions: Anders J Skanderup/GIS

Name of Journal, Conference Books or Other Publications: Nature Communications

Publication DOI: https://doi.org/10.1038/s41467-021-22463-y

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Guanhua Zhu (GIS), Yu A. Guo (GIS), Danliang Ho (GIS), Polly Poon (GIS), Zhong Wee Poh (GIS), Pui Mun Wong (GIS), Anna Gan (GIS), Mei Mei Chang (GIS), Dimitrios Kleftogiannis (GIS), Yi Ting Lau (GIS), Brenda Tay NCCS), Wan Jun Lim NCCS), Clarinda Chua NCCS), Tira J. Tan NCCS), Si-Lin Koo NCCS), Dawn Q. Chong NCCS), Yoon Sim Yap NCCS), Iain Tan NCCS), Sarah Ng (GIS) & Anders J. Skanderup (GIS)

Link to article in Journal: https://www.nature.com/articles/s41467-021-22463-y

Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer

Published Date: 01-Apr-2021
Name of Corresponding Authors and Institutions: Elena Levantini (Harvard Medical School); Daniel G Tenen (Cancer Science Institute of Singapore, National University of Singapore)

Name of Journal, Conference Books or Other Publications: Communications Biology

Publication DOI: DOI: 10.1038/s42003-021-01897-6

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Giorgia Maroni (NUS), Mahmoud A Bassal (NUS), Indira Krishnan (HMS), Chee Wai Fhu (NUS), Virginia Savova (HMS), Rapolas Zilionis (HMS), Valerie A Maymi (BIDMC), Nicole Pandell (BIDMC), Eva Csizmadia (BIDMC), Junyan Zhang (HMC), Barbara Storti (NEST), Julio Castaño (BST), Riccardo Panella (HMS), Jia Li (NUS), Corinne E Gustafson (BWH), Sam Fox (BWH), Rachel D Levy (BWH), Claire V Meyerovitz (BWH), Peter J Tramontozzi (BWH), Kimberly Vermilya (BWH), Assunta De Rienzo (HMS), Stefania Crucitta (UoP), Daniela S Bassères (UOSP), Marla Weetall (PTC), Art Branstrom (PTC), Alessandra Giorgetti (UOB), Raffaele Ciampi (UOHP), Marzia Del Re (UHOP), Romano Danesi (UOP), Ranieri Bizzarri (NEST), Henry Yang (NUS), Olivier Kocher (HMS), Allon M Klein (HMS), Robert S Welner (UoA), Raphael Bueno (HMS), Maria Cristina Magli (HMS), John G Clohessy (HMS), Azhar Ali (NUS), Daniel G Tenen (NUS, HMS), Elena Levantini (HMS)

Link to article in Journal: https://www.nature.com/articles/s42003-021-01897-6

Pan-Cancer Analysis of Ligand-Receptor Cross-talk in the Tumor Microenvironment

Published Date: 01-Apr-2021
Name of Corresponding Authors and Institutions: Anders J Skanderup/GIS

Name of Journal, Conference Books or Other Publications: Cancer Research

Publication DOI: doi: 10.1158/0008-5472.CAN-20-2352

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Umesh Ghoshdastider, Neha Rohatgi, Marjan Mojtabavi Naeini, Probhonjon Baruah, Egor Revkov, Yu Amanda Guo, Simone Rizzetto, Angeline M.L. Wong, Sundar Solai, Tin T. Nguyen, Joe Poh Sheng Yeong, Jabed Iqbal, Puay Hoon Tan, Balram Chowbay, Ramanuj Dasgupta and Anders J. Skanderup

Link to article in Journal: https://cancerres.aacrjournals.org/content/81/7/1802.long

Novel Therapies for Metastatic Non-Small Cell Lung Cancer with MET Exon 14 Alterations: A Spotlight on Capmatinib

Published Date: 18-Mar-2021
Name of Corresponding Authors and Institutions: Dr Daniel Tan, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Lung Cancer

Publication DOI: doi: 10.2147/LCTT.S263610

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Aaron C Tan, Tracy J Loh, Xue Lin Kwang, Gek San Tan, Kiat Hon Lim, Daniel SW Tan

Link to article in Journal: https://www.dovepress.com/novel-therapies-for-metastatic-non-small-cell-lung-cancer-with-met-exo-peer-reviewed-fulltext-article-LCTT

Novel Therapies for Metastatic Non-Small Cell Lung Cancer with MET Exon 14 Alterations: A Spotlight on Capmatinib

Published Date: 18-Mar-2021
Name of Corresponding Authors and Institutions: Dr Daniel Tan, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Lung Cancer

Publication DOI: doi: 10.2147/LCTT.S263610

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Aaron C Tan, Tracy J Loh, Xue Lin Kwang, Gek San Tan, Kiat Hon Lim, Daniel SW Tan

Link to article in Journal: https://www.dovepress.com/novel-therapies-for-metastatic-non-small-cell-lung-cancer-with-met-exo-peer-reviewed-fulltext-article-LCTT

Mechanisms of resistance to selective RET tyrosine kinase inhibitors in RET fusion-positive non-small-cell lung cancer

Published Date: Dec-2020
Name of Corresponding Authors and Institutions: J.F. Gainor (Massachusetts General Hospital)

Name of Journal, Conference Books or Other Publications: Annals of Oncology

Publication DOI: doi: 10.1016/j.annonc.2020.09.015

Name of All Authors/Co-Authors and Institutions according to authorship order as published: J.J. Lin, S.V. Liu, C.E. McCoach, V.W. Zhu, A.C. Tan, S. Yoda, J. Peterson, A. Do, K. Prutisto-Chang, I. Dagogo-Jack, L.V. Sequist, L.J. Wirth, J.K. Lennerz, A.N. Hata, M. Mino-Kenudson, V. Nardi, S.-H.I. Ou, D.S.-W. Tan, J.F. Gainor

Link to article in Journal: https://www.annalsofoncology.org/article/S0923-7534(20)42465-2/fulltext

Partial absence of PD-1 expression by tumor-infiltrating EBV-specific CD8+ T cells in EBV-driven lymphoepithelioma-like carcinoma

Published Date: 09-Sep-2020
Name of Corresponding Authors and Institutions: Evan W Newell, SIgN, A*STAR

Name of Journal, Conference Books or Other Publications: Clinical & Translational Immunology

Publication DOI: https://doi.org/10.1002/cti2.1175

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Yannick Simoni (SIGN), Etienne Becht (SIGN), Shamin Li (SIGN), Chiew Yee Loh (SIGN), Joe Poh Sheng Yeong (SGH), Tony Kiat Hon Lim (SGH), Angela Takano (SGH), Daniel Shao Weng Tan (NCCS), Evan W Newell (SIGN)

Link to article in Journal: https://onlinelibrary.wiley.com/doi/10.1002/cti2.1175

High-Dimensional Characterization of the Systemic Immune Landscape Informs on Synergism Between Radiation Therapy and Immune Checkpoint Blockade

Published Date: Sep-2020
Name of Corresponding Authors and Institutions: Evan W Newell, SIgN, A*STAR; Melvin Chua, NCCS

Name of Journal, Conference Books or Other Publications: International Journal of Radiation Oncology, Biology, Physics

Publication DOI: doi: 10.1016/j.ijrobp.2020.06.007

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Kevin L M Chua, Michael Fehlings, Eugenia L L Yeo, Alessandra Nardin, Hermi Sumatoh, Pek Lim Chu, Wen-Long Nei, Enya H W Ong, Wai Yee Woo, Kar Perng Low, Haitao Wang, Dennis J J Poon, Zhong-Guo Liang, Kai Yao, Luo Huang, Chee Keong Toh, Mei-Kim Ang, Mohamad Farid, Xin Min Cheng, Ravindran Kanesvaran, Rebecca Dent, Joseph T S Wee, Tony K H Lim, N Gopalakrishna Iyer, Daniel S W Tan, Khee Chee Soo, Evan W Newell, Melvin L K Chua

Link to article in Journal: https://www.redjournal.org/article/S0360-3016(20)31248-7/fulltext

Molecular Characterization and Clinical Outcomes in RET-Rearranged NSCLC

Published Date: 28-Aug-2020
Name of Corresponding Authors and Institutions: Dr Daniel Tan, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Journal of Thoracic Oncology

Publication DOI: DOI: 10.1016/j.jtho.2020.08.011

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Tan AC (NCCS), Seet AOL (NCCS), Lai GGY (NCCS), Lim TH (SGH), Lim AST (SGH), Tan GS (SGH), Takano A (SGH), Tai DWM (NCCS), Tan TJY (NCCS), Lam JYC (NCCS), Ng MCH (NCCS), Tan WL (NCCS), Ang MK (NCCS), Kanesvaran R (NCCS), Ng QS (NCCS), Jain A (NCCS), Rajasekaran T (NCCS), Lim WT (NCCS), Tan EH (NCCS), Lim TKH (SGH), Tan DSW (NCCS)

Link to article in Journal: https://www.jto.org/article/S1556-0864(20)30671-7/fulltext

Genomic landscape and ethnic specificity of lung adenocarcinoma in Asia

Published Date: 01-Feb-2020
Name of Corresponding Authors and Institutions: Tan DSW, National Cancer Centre Singapore; Zhai Weiwei, Genome Institute of Singapore

Name of Journal, Conference Books or Other Publications: Nature Genetics

Publication DOI: https://doi.org/10.1038/s41588-019-0569-6

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Jianbin Chen (GIS), Hechuan Yang (GIS), Audrey Su Min Teo (GIS), Lidyana Bte Amer (GIS), Faranak Ghazi Sherbaf (GIS), Chu Quan Tan (GIS), Jacob Josiah Santiago Alvarez (GIS), Bingxin Lu (GIS), Jia Qi Lim (GIS), Angela Takano (SGH), Rahul Nahar (GIS), Yin Yeng Lee (GIS), Cheryl Zi Jin Phua (GIS), Khi Pin Chua (GIS), Lisda Suteja (NCCS), Pauline Jieqi Chen (GIS), Mei Mei Chang (GIS), Tina Puay Theng Koh (NCCS), Boon-Hean Ong (NHCS), Devanand Anantham (SGH), Anne Ann Ling Hsu (SGH), Apoorva Gogna (SGH), Chow Wei Too (SGH), Zaw Win Aung (NCCS), Yi Fei Lee (GIS), Lanying Wang(NCCS), Tony Kiat Hon Lim (SGH), Andreas Wilm (GIS), Poh Sum Choi (GIS), Poh Yong Ng (GIS), Chee Keong Toh (NCCS), Wan-Teck Lim (NCCS), Siming Ma (GIS), Bing Lim (GIS), Jin Liu (Duke-NUS), Wai Leong Tam (GIS), Anders Jacobsen Skanderup (GIS), Joe Poh Sheng Yeong (SGH), Eng-Huat Tan (NCCS), Caretha L. Creasy (GSK), Daniel Shao Weng Tan (NCCS), Axel M. Hillmer (GIS) and Weiwei Zhai (GIS)

Link to article in Journal: https://www.nature.com/articles/s41588-019-0569-6

Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1-2 trial

Published Date: Feb-2020

Name of Journal, Conference Books or Other Publications: The Lancet Oncology

Publication DOI: doi: 10.1016/S1470-2045(19)30690-4

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Drilon A, Siena S, Dziadziuszko R, Barlesi F, Krebs MG, Shaw AT, de Braud F, Rolfo C, Ahn MJ, Wolf J, Seto T, Cho BC, Patel MR, Chiu CH, John T, Goto K, Karapetis CS, Arkenau HT, Kim SW, Ohe Y, Li YC, Chae YK, Chung CH, Otterson GA, Murakami H, Lin CC, Tan DSW, Prenen H, Riehl T, Chow-Maneval E, Simmons B, Cui N, Johnson A, Eng S, Wilson TR, Doebele RC; trial investigators

Link to article in Journal: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30690-4/fulltext

TRANSCOMPP: Understanding phenotypic plasticity by estimating Markov transition rates for cell state transitions.

Published Date: 23-Jan-2020
Name of Corresponding Authors and Institutions: L Tucker-Kellogg, Duke-NUS

Name of Journal, Conference Books or Other Publications: Bioinformatics

Publication DOI: doi: 10.1093/bioinformatics/btaa021.

Name of All Authors/Co-Authors and Institutions according to authorship order as published: NS Jagannathan (Duke-NUS), MO Ihsan (NUS), XX Kin (NUS), RE Welsch (Massachusetts Institute of Technology), MV Clément (NUS), L Tucker-Kellogg (Duke-NUS).

Link to article in Journal: https://academic.oup.com/bioinformatics/article/36/9/2813/5714733

Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and cost-effectiveness analysis

Published Date: 26-Nov-2019
Name of Corresponding Authors and Institutions: Dr Daniel Tan, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Lung Cancer

Publication DOI: doi: 10.1016/j.lungcan.2019.11.022

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Tan AC (NCCS), Lai GGY (NCCS), Tan GS (SGH), Poon SY (NCCS), Doble B (Duke-NUS), Lim TH (SGH), Aung ZW (NCCS), Takano A (SGH), Tan WL (NCCS), Ang MK (NCCS), Tan BS (SGH), Devenand A (SGH), Too CW (SGH), Gogna A (SGH), Ong BH, Koh TPT (NCCS), Kanesvaran R, Ng QS (NCCS), Jain A (NCCS), Rajasekaran T (NCCS), Lim AST (SGH), Lim WT (NCCS), Toh CK (NCCS), Tan EH (NCCS), Lim TKH (SGH), Tan DSW (NCCS)

Link to article in Journal: https://www.lungcancerjournal.info/article/S0169-5002(19)30747-0/fulltext

Third generation EGFR TKI landscape for metastatic EGFR mutant non-small cell lung cancer

Published Date: Jun-2019
Name of Corresponding Authors and Institutions: Daniel S. W. Tan, NCCS

Name of Journal, Conference Books or Other Publications: Expert Review of Anticancer Therapy

Publication DOI: doi: 10.1080/14737140.2019.1604228

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Aaron C. Tan,Yi Lin Teh,Gillianne G. Y. Lai &Daniel S. W. Tan

Link to article in Journal: https://www.tandfonline.com/doi/full/10.1080/14737140.2019.1604228

Single cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species

Published Date: 21-May-2019
Name of Corresponding Authors and Institutions: Mikael J. Pittet, Massachusetts General Hospital Research Institute and Harvard Medical School. Virginia Savova, Harvard Medical School and Immunology and Inflammation Therapeutic Area, Sanofi. Allon M. Klein, Harvard Medical School

Name of Journal, Conference Books or Other Publications: Immunity

Publication DOI: 10.1016/j.immuni.2019.03.009

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Rapolas Zilionis (Harvard Medical School), Camilla Engblom (Harvard Medical School), Christina Pfirschke (Harvard Medical School), Virginia Savova (Harvard Medical School), David Zemmour (Harvard Medical School), Hatice D. Saatcioglu (Harvard Medical School), Indira Krishnan (Harvard Medical School), Giorgia Maroni (Harvard Medical School), Claire V.Meyerovitz (Harvard Medical School), Clara M. Kerwin (Harvard Medical School), Sun Choi (Harvard Medical School), William G. Richards (Harvard Medical School), Assunta De Rienzo (Harvard Medical School), Daniel G Tenen (Harvard Medical Schoo, CSI/NUS), Raphael Bueno (Harvard Medical School), Elena Levantini (Harvard Medical School), Mikael J. Pittet (Harvard Medical School), Allon M. Klein (Harvard Medical School)

Link to article in Journal: https://www.cell.com/immunity/fulltext/S1074-7613(19)30126-8

Methionine is a metabolic dependency of tumor-initiating cells

Published Date: 06-May-2019
Name of Corresponding Authors and Institutions: Bing Lim, Merck Sharp and Dohme Translational Medicine Research Centre, Singapore; Wai Leong Tam, Genome Institute of Singapore

Name of Journal, Conference Books or Other Publications: Nature Medicine

Publication DOI: doi: 10.1038/s41591-019-0423-5

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Zhenxun Wang (GIS), Lian Yee Yip (BTI), Jia Hui Jane Lee (GIS), Zhengwei Wu (GIS), Hui Yi Chew (GIS), Pooi Kiat William Chong (BTI), Chin Chye Teo (BTI), Heather Yin-Kuan Ang (GIS), Kai Lay Esther Peh (BTI), Ju Yuan (GIS), Siming Ma (GIS), Li Shi Kimberly Choo (GIS), Nurhidayah Basri, Xia Jiang (BTI), Qiang Yu (GIS), Axel M. Hillmer (GIS), Wan Teck Lim (NCCS), Tony Kiat Hon Lim (SGH), Angela Takano (SGH), Eng Huat Tan (NCCS), Daniel Shao Weng Tan (NCCS), Ying Swan Ho (BII), Bing Lim (GIS) & Wai Leong Tam (GIS)

Link to article in Journal: https://www.nature.com/articles/s41591-019-0423-5

Clonal MET amplification as a determinant of tyrosine kinase inhibitor resistance in Epidermal Growth Factor Receptor-Mutant non-small cell lung cancer

Published Date: Apr-2019
Name of Corresponding Authors and Institutions: Dr Daniel Tan, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Journal of Clinical Oncology

Publication DOI: doi: 10.1200/JCO.18.00177

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Gillianne G.Y. Lai, Tse Hui Lim, John Lim, Perry J.R. Liew, Xue Lin Kwang, Rahul Nahar, Zaw Win Aung, Angela Takano, Yin Yeng Lee, Dawn P.X. Lau, Gek San Tan, Sze Huey Tan, Wan Ling Tan, Mei-Kim Ang, Chee Keong Toh, Bien Soo Tan, Anantham Devanand, Chow Wei Too, Apoorva Gogna, Boon Hean Ong, Tina P.T. Koh, Ravindran Kanesvaran, Quan Sing Ng, Amit Jain, Tanujaa Rajasekaran, Ju Yuan, Tony Kiat Hon Lim, Alvin S.T. Lim, Axel M. Hillmer, Wan Teck Lim, N. Gopalakrishna Iyer, Wai Leong Tam, Weiwei Zhai, Eng-Huat Tan, and Daniel S.W. Tan

Link to article in Journal: https://ascopubs.org/doi/10.1200/JCO.18.00177

Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer

Published Date: 27-Feb-2019
Name of Corresponding Authors and Institutions: Tan DSW, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Journal of Clinical Oncology

Publication DOI: DOI: 10.1200/JCO.18.00177

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Gillianne G Y Lai, Tse Hui Lim, John Lim, Perry J R Liew, Xue Lin Kwang, Rahul Nahar, Zaw Win Aung, Angela Takano, Yin Yeng Lee, Dawn P X Lau, Gek San Tan, Sze Huey Tan, Wan Ling Tan, Mei-Kim Ang, Chee Keong Toh, Bien Soo Tan, Anantham Devanand, Chow Wei Too, Apoorva Gogna, Boon Hean Ong, Tina P T Koh, Ravindran Kanesvaran, Quan Sing Ng, Amit Jain, Tanujaa Rajasekaran, Ju Yuan, Tony Kiat Hon Lim, Alvin S T Lim, Axel M Hillmer, Wan Teck Lim, N Gopalakrishna Iyer, Wai Leong Tam, Weiwei Zhai, Eng-Huat Tan, Daniel S W Tan

Link to article in Journal: https://ascopubs.org/doi/10.1200/JCO.18.00177?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

A Decade of Never-smokers Among Lung Cancer Patients-Increasing Trend and Improved Survival

Published Date: Sep-2018
Name of Corresponding Authors and Institutions: Eng-Huat Tan (NCCS)

Name of Journal, Conference Books or Other Publications: Clinical Lung Cancer

Publication DOI: doi: 10.1016/j.cllc.2018.03.013

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Chee-Keong Toh, Whee-Sze Ong, Wan-Teck Lim, Daniel Shao-Weng Tan, Quan-Sing Ng, Ravindran Kanesvaran, Wei-Jie Seow, Mei-Kim Ang, Eng-Huat Tan

Link to article in Journal: https://www.clinical-lung-cancer.com/article/S1525-7304(18)30055-X/fulltext

Bystander CD8 + T cells are abundant and phenotypically distinct in human tumour infiltrates

Published Date: May-2018
Name of Corresponding Authors and Institutions: Evan W Newell, SIgN, A*STAR

Name of Journal, Conference Books or Other Publications: Nature

Publication DOI: doi: 10.1038/s41586-018-0130-2.

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Yannick Simoni, Etienne Becht, Michael Fehlings, Chiew Yee Loh, Si-Lin Koo, Karen Wei Weng Teng, Joe Poh Sheng Yeong, Rahul Nahar, Tong Zhang, Hassen Kared, Kaibo Duan, Nicholas Ang, Michael Poidinger, Yin Yeng Lee, Anis Larbi, Alexis J. Khng, Emile Tan, Cherylin Fu, Ronnie Mathew, Melissa Teo, Wan Teck Lim, Chee Keong Toh, Boon-Hean Ong, Tina Koh, Axel M. Hillmer, Angela Takano, Tony Kiat Hon Lim, Eng Huat Tan, Weiwei Zhai, Daniel S. W. Tan, Iain Beehuat Tan & Evan W. Newell

Link to article in Journal: https://www.nature.com/articles/s41586-018-0130-2

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing

Published Date: 15-Jan-2018
Name of Corresponding Authors and Institutions: Axel M. Hillmer (GIS); Tan DSW, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: Nature Communications

Publication DOI: https://doi.org/10.1038/s41467-017-02584-z

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Rahul Nahar, Weiwei Zhai, Tong Zhang, Angela Takano, Alexis J. Khng, Yin Yeng Lee, Xingliang Liu, Chong Hee Lim, Tina P. T. Koh, Zaw Win Aung, Tony Kiat Hon Lim, Lavanya Veeravalli, Ju Yuan, Audrey S. M. Teo, Cheryl X. Chan, Huay Mei Poh, Ivan M. L. Chua, Audrey Ann Liew, Dawn Ping Xi Lau, Xue Lin Kwang, Chee Keong Toh, Wan-Teck Lim, Bing Lim, Wai Leong Tam, Eng-Huat Tan, Axel M. Hillmer & Daniel S. W. Tan

Link to article in Journal: https://www.nature.com/articles/s41467-017-02584-z

A systematic review and meta-analysis of individual patient data on the impact of the BIM deletion polymorphism on treatment outcomes in epidermal growth factor receptor mutant lung cancer

Published Date: Jun-2017
Name of Corresponding Authors and Institutions: Wan Teck Lim (NCCS)

Name of Journal, Conference Books or Other Publications: Oncotarget

Publication DOI: doi: 10.18632/oncotarget.17102

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Soh, Sheila X., Fahad J. Siddiqui, John C. Allen, Go Woon Kim, Jae Cheol Lee, Yasushi Yatabe, Manabu Soda, Hiroyuki Mano, Ross A. Soo, Tan-Min Chin, Hiromichi Ebi, Seiji Yano, Keitaro Matsuo, Xiaomin Niu, Shun Lu, Kazutoshi Isobe, Jih-Hsiang Lee, James C. Yang, Mingchuan Zhao, Caicun Zhou, June-Koo Lee, Se-Hoon Lee, Ji Yun Lee, Myung-Ju Ahn, Tira J. Tan, Daniel S. Tan, Eng-Huat Tan, S. Tiong Ong, and Wan-Teck Lim.

Link to article in Journal: https://www.oncotarget.com/article/17102/text/

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

Published Date: 17-Jan-2017
Name of Corresponding Authors and Institutions: Evan W Newell, SIgN, A*STAR

Name of Journal, Conference Books or Other Publications: Immunity

Publication DOI: doi: 10.1016/j.immuni.2016.11.005

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Yannick Simoni, Michael Fehlings, Henrik N. Kløverpris, Naomi McGovern, Si-Lin Koo, Chiew Yee Loh, Shawn Lim, Ayako Kurioka, Joannah R. Fergusson, Choong-Leong Tang, Ming Hian Kam, Koh Dennis, Tony Kiat Hon Lim, Alexander Chung Yaw Fui, Chan Weng Hoong, Jerry Kok Yen Chan, Maria Curotto de Lafaille, Sriram Narayanan, Sonia Baig, Muhammad Shabeer, Sue-Anne Ee Shiow Toh, Henry Kun Kiaang Tan, Rosslyn Anicete, Eng-Huat Tan, Angela Takano, Paul Klenerman, Alasdair Leslie, Daniel S.W. Tan, Iain Beehuat Tan, Florent Ginhoux, Evan W. Newell

Link to article in Journal: https://www.cell.com/immunity/fulltext/S1074-7613(16)30477-0

A High-Dimensional Atlas of Human T Cell Diversity Reveals Tissue-Specific Trafficking and Cytokine Signatures

Published Date: 16-Aug-2016
Name of Corresponding Authors and Institutions: Evan W Newell, SIgN, A*STAR

Name of Journal, Conference Books or Other Publications: Immunity

Publication DOI: doi: 10.1016/j.immuni.2016.07.007

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Michael Thomas Wong, David Eng Hui Ong, Frances Sheau Huei Lim, Karen Wei Weng Teng, Naomi McGovern, Sriram Narayanan, Wen Qi Ho, Daniela Cerny, Henry Kun Kiaang Tan, Rosslyn Anicete, Bien Keem Tan, Tony Kiat Hon Lim, Chung Yip Chan, Peng Chung Cheow, Ser Yee Lee, Angela Takano, Eng-Huat Tan, John Kit Chung Tam, Ern Yu Tan, Jerry Kok Yen Chan, Katja Fink, Antonio Bertoletti, Florent Ginhoux, Maria Alicia Curotto de Lafaille, Evan William Newell

Link to article in Journal: https://www.cell.com/immunity/fulltext/S1074-7613(16)30280-1

Novel therapeutic targets on the horizon for lung cancer

Published Date: 1-Aug-2016
Name of Corresponding Authors and Institutions: Tan DSW, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: The Lancet Oncology

Publication DOI: https://doi.org/10.1016/S1470-2045(16)30123-1

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Wan-Ling Tan, Amit Jain, Angela Takano, Evan W Newell, N Gopalakrishna Iyer, Wan-Teck Lim, Eng-Huat Tan, Weiwei Zhai, Axel M Hillmer, Wai-Leong Tam, Daniel S W Tan

Link to article in Journal: https://linkinghub.elsevier.com/retrieve/pii/S1470-2045(16)30123-1

Single-cell multimodal profiling reveals cellular epigenetic heterogeneity

Published Date: Aug-2016
Name of Corresponding Authors and Institutions: Stephen R Quake, Stanford University, Stanford, California & William F Burkholder, IMCB, A*STAR

Name of Journal, Conference Books or Other Publications: Nature Methods

Publication DOI: doi: 10.1038/nmeth.3961

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Lih Feng Cheow, Elise T Courtois, Yuliana Tan, Ramya Viswanathan, Qiaorui Xing, Rui Zhen Tan, Daniel S W Tan, Paul Robson, Yuin-Han Loh, Stephen R Quake & William F Burkholder

Link to article in Journal: https://www.nature.com/articles/nmeth.3961

Single-cell profiling approaches to probing tumor heterogeneity

Published Date: Jul-2016
Name of Corresponding Authors and Institutions: Chwee Teck Lim (NUS); Majid Ebrahimi Warkiani (SMART centre, Singapore)

Name of Journal, Conference Books or Other Publications: International Journal of Cancer

Publication DOI: doi: 10.1002/ijc.30006

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Bee Luan Khoo,Parthiv Kant Chaudhuri,Naveen Ramalingam,Daniel Shao Weng Tan,Chwee Teck Lim,Majid Ebrahimi Warkiani

Link to article in Journal: https://onlinelibrary.wiley.com/doi/10.1002/ijc.30006

Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression

Published Date: 21-Jun-2016
Name of Corresponding Authors and Institutions: Wai Leong Tam, CSI/GIS

Name of Journal, Conference Books or Other Publications: Nature Communications

Publication DOI: https://doi.org/10.1038/ncomms11702

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Wen Cai Zhang, Tan Min Chin, Henry Yang, Min En Nga, Declan Patrick Lunny, Edwin Kok Hao Lim, Li Li Sun, Yin Huei Pang, Yi Ning Leow, Shanneen Rossellini Y Malusay, Priscilla Xin Hui Lim, Jeravan Zili Lee, Benedict Jian Wei Tan, Ng Shyh-Chang, Elaine Hsuen Lim, Wan Teck Lim, Daniel Shao Weng Tan, Eng Huat Tan, Bee Choo Tai, Ross Andrew Soo, Wai Leong Tam & Bing Lim

Link to article in Journal: https://www.nature.com/articles/ncomms11702

Microfluidic enrichment for the single cell analysis of circulating tumor cells

Published Date: 29-Feb-2016
Name of Corresponding Authors and Institutions: Wan-Teck Lim, NCCS; Chwee Teck Lim, NUS

Name of Journal, Conference Books or Other Publications: Scientific Reports

Publication DOI: doi: 10.1038/srep22076.

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Trifanny Yeo, Swee Jin Tan, Chew Leng Lim, Dawn Ping Xi Lau, Yong Wei Chua, Sai Sakktee Krisna, Gopal Iyer, Gek San Tan, Tony Kiat Hon Lim, Daniel S.W. Tan, Wan-Teck Lim & Chwee Teck Lim

Link to article in Journal: https://www.nature.com/articles/srep22076

Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Published Date: 8-May-2015
Name of Corresponding Authors and Institutions: Dr Daniel Tan, National Cancer Centre Singapore

Name of Journal, Conference Books or Other Publications: PLoS One

Publication DOI: doi: 10.1371/journal.pone.0123587

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Amit Jain, Cindy Lim, Eugene MingJin Gan, David Zhihao Ng, Quan Sing Ng, Mei Kim Ang, Angela Takano, Kian Sing Chan, Wu Meng Tan, Ravindran Kanesvaran, Chee Keong Toh, Chian Min Loo, Anne Ann Ling Hsu, Anantham Devanand, Chong Hee Lim, Heng Nung Koong, Tina Koh, Kam Weng Fong, Swee Peng Yap, Su Woon Kim, Balram Chowbay, Lynette Oon, Kiat Hon Lim, Wan Teck Lim, Eng Huat Tan, Daniel Shao Weng Tan

Link to article in Journal: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123587

Intertumour heterogeneity of non-small cell lung carcinomas revealed by multiplexed mutation profiling and integrative genomics

Published Date: Sep-2014
Name of Corresponding Authors and Institutions: Philippe Broët, INSERM UMR669, Villejuif, France

Name of Journal, Conference Books or Other Publications: International Journal of Cancer

Publication DOI: doi: 10.1002/ijc.28750

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Daniel S W Tan, Sophie Camilleri-Broët, Eng Huat Tan, Marco Alifano, Wan-Teck Lim, Antonio Bobbio, Shenli Zhang, Quan-Sing Ng, Mei-Kim Ang, N Gopalakrishna Iyer, Angela Takano, Kiat Hon Lim, Jean-François Régnard, Patrick Tan, Philippe Broët

Link to article in Journal: https://onlinelibrary.wiley.com/doi/10.1002/ijc.28750

Isolation and retrieval of circulating tumor cells using centrifugal forces

Published Date: Feb-2013
Name of Corresponding Authors and Institutions: Chwee Teck Lim (NUS)

Name of Journal, Conference Books or Other Publications: Scientific Reports

Publication DOI: doi: 10.1038/srep01259

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Han Wei Hou, Majid Ebrahimi Warkiani, Bee Luan Khoo, Zi Rui Li, Ross A. Soo, Daniel Shao-Weng Tan, Wan-Teck Lim, Jongyoon Han, Ali Asgar S. Bhagat & Chwee Teck Lim

Link to article in Journal: https://www.nature.com/articles/srep01259

A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer

Published Date: 18-Mar-2012
Name of Corresponding Authors and Institutions: Wan-Teck Lim, NCCS; Yijun Ruan, GIS; S Tiong Ong, NCCS

Name of Journal, Conference Books or Other Publications: Nature Medicine

Publication DOI: doi: 10.1038/nm.2713

Name of All Authors/Co-Authors and Institutions according to authorship order as published: King Pan Ng, Axel M Hillmer, Charles T H Chuah, Wen Chun Juan, Tun Kiat Ko, Audrey S M Teo, Pramila N Ariyaratne, Naoto Takahashi, Kenichi Sawada, Yao Fei, Sheila Soh, Wah Heng Lee, John W J Huang, John C Allen Jr, Xing Yi Woo, Niranjan Nagarajan, Vikrant Kumar, Anbupalam Thalamuthu, Wan Ting Poh, Ai Leen Ang, Hae Tha Mya, Gee Fung How, Li Yi Yang, Liang Piu Koh, Balram Chowbay, Chia-Tien Chang, Veera S Nadarajan, Wee Joo Chng, Hein Than, Lay Cheng Lim, Yeow Tee Goh, Shenli Zhang, Dianne Poh, Patrick Tan, Ju-Ee Seet, Mei-Kim Ang, Noan-Minh Chau, Quan-Sing Ng, Daniel S W Tan, Manabu Soda, Kazutoshi Isobe, Markus M Nöthen, Tien Y Wong, Atif Shahab, Xiaoan Ruan, Valère Cacheux-Rataboul, Wing-Kin Sung, Eng Huat Tan, Yasushi Yatabe, Hiroyuki Mano, Ross A Soo, Tan Min Chin, Wan-Teck Lim, Yijun Ruan & S Tiong Ong

Link to article in Journal: https://www.nature.com/articles/nm.2713

Clinical Trials

Efficacy of Selpercatinib in RET Fusion-Positive Non-Small-Cell Lung Cancer

Published Date: Aug-2020
Name of Corresponding Authors and Institutions: VIvek Subbiah

Name of Journal, Conference Books or Other Publications: New England Journal of Medicine

Publication DOI: doi: 10.1056/NEJMoa2005653

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Drilon A, Oxnard GR, Tan DSW, Loong HHF, Johnson M, Gainor J, McCoach CE, Gautschi O, Besse B, Cho BC, Peled N, Weiss J, Kim YJ, Ohe Y, Nishio M, Park K, Patel J, Seto T, Sakamoto T, Rosen E, Shah MH, Barlesi F, Cassier PA, Bazhenova L, De Braud F, Garralda E, Velcheti V, Satouchi M, Ohashi K, Pennell NA, Reckamp KL, Dy GK, Wolf J, Solomon B, Falchook G, Ebata K, Nguyen M, Nair B, Zhu EY, Yang L, Huang X, Olek E, Rothenberg SM, Goto K, Subbiah V

Link to article in Journal: https://www.nejm.org/doi/10.1056/NEJMoa2005653

Capmatinib in MET Exon 14-Mutated or MET-Amplified Non-Small-Cell Lung Cancer

Published Date: Sep-2020

Name of Journal, Conference Books or Other Publications: New England Journal of Medicine

Publication DOI: doi: 10.1056/NEJMoa2002787

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Wolf J, Seto T, Han JY, Reguart N, Garon EB, Groen HJM, Tan DSW, Hida T, de Jonge M, Orlov SV, Smit EF, Souquet PJ, Vansteenkiste J, Hochmair M, Felip E, Nishio M, Thomas M, Ohashi K, Toyozawa R, Overbeck TR, de Marinis F, Kim TM, Laack E, Robeva A, Le Mouhaer S, Waldron-Lynch M, Sankaran B, Balbin OA, Cui X, Giovannini M, Akimov M, Heist RS; GEOMETRY mono-1 Investigators.

Link to article in Journal: https://www.nejm.org/doi/10.1056/NEJMoa2002787

Tepotinib plus gefitinib in patients with EGFR-mutant non-small-cell lung cancer with MET overexpression or MET amplification and acquired resistance to previous EGFR inhibitor (INSIGHT study): an open-label, phase 1b/2, multicentre, randomised trial

Published Date: Nov-2020

Name of Journal, Conference Books or Other Publications: The Lancet. Respiratory Medicine

Publication DOI: doi: 10.1016/S2213-2600(20)30154-5

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Wu YL, Cheng Y, Zhou J, Lu S, Zhang Y, Zhao J, Kim DW, Soo RA, Kim SW, Pan H, Chen YM, Chian CF, Liu X, Tan DSW, Bruns R, Straub J, Johne A, Scheele J, Park K, Yang JC; INSIGHT Investigators.

Link to article in Journal: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30154-5/fulltext

Safety and efficacy of nazartinib (EGF816) in adults with EGFR-mutant non-small-cell lung carcinoma: a multicentre, open-label, phase 1 study

Published Date: Jun-2020

Name of Journal, Conference Books or Other Publications: The Lancet. Respiratory Medicine

Publication DOI: doi: 10.1016/S2213-2600(19)30267-X

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Tan DS, Leighl NB, Riely GJ, Yang JC, Sequist LV, Wolf J, Seto T, Felip E, Aix SP, Jonnaert M, Pan C, Tan EY, Ko J, Moody SE, Kim DW

Link to article in Journal: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(19)30267-X/fulltext

Ceritinib plus Nivolumab in Patients with Advanced ALK-Rearranged Non-Small Cell Lung Cancer: Results of an Open-Label, Multicenter, Phase 1B Study

Published Date: Mar-2020

Name of Journal, Conference Books or Other Publications: Journal of Thoracic Oncology

Publication DOI: doi: 10.1016/j.jtho.2019.10.006

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Felip E, de Braud FG, Maur M, Loong HH, Shaw AT, Vansteenkiste JF, John T, Liu G, Lolkema MP, Selvaggi G, Giannone V, Cazorla P, Baum J, Balbin OA, Wang LV, Lau YY, Scott JW, Tan DS

Link to article in Journal: https://www.jto.org/article/S1556-0864(19)33564-6/fulltext

Phase 1/2 study of ceritinib in Chinese patients with advanced anaplastic lymphoma kinase-rearranged non-small cell lung cancer previously treated with crizotinib: Results from ASCEND-6

Published Date: Dec-2020

Name of Journal, Conference Books or Other Publications: Lung Cancer

Publication DOI: doi: 10.1016/j.lungcan.2020.10.024

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Wu YL, Shi Y, Tan DSW, Xiaoqing L, Cheng Y, Zhou J, An TT, Lu Y, Zhu B, Bai C, Passos VQ, Lau YY, Xun L, Zhang L.

Link to article in Journal: https://www.lungcancerjournal.info/article/S0169-5002(20)30677-2/fulltext

Phase Ib Study of Combination Therapy with MEK Inhibitor Binimetinib and Phosphatidylinositol 3-Kinase Inhibitor Buparlisib in Patients with Advanced Solid Tumors with RAS/RAF Alterations

Published Date: Jan-2020

Name of Journal, Conference Books or Other Publications: The Oncologist

Publication DOI: doi: 10.1634/theoncologist.2019-0297

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Bardia A, Gounder M, Rodon J, Janku F, Lolkema MP, Stephenson JJ, Bedard PL, Schuler M, Sessa C, LoRusso P, Thomas M, Maacke H, Evans H, Sun Y, Tan DSW

Link to article in Journal: https://theoncologist.onlinelibrary.wiley.com/doi/full/10.1634/theoncologist.2019-0297

Characterization and phase I study of CLR457, an orally bioavailable pan-class I PI3-kinase inhibitor

Published Date: Apr-2019

Name of Journal, Conference Books or Other Publications: Investigational New Drugs

Publication DOI: doi: 10.1007/s10637-018-0627-4

Name of All Authors/Co-Authors and Institutions according to authorship order as published: James J. Harding, Todd M. Bauer, Daniel S. W. Tan, Philippe L. Bedard, Jordi Rodon, Toshihiko Doi, Christian Schnell, Varsha Iyer, Fabienne Baffert, Rajkumar Radhakrishnan, Claire Fabre & Dejan Juric

Link to article in Journal: https://link.springer.com/article/10.1007%2Fs10637-018-0627-4

Clinical Practice Guidelines

Pan-Asian adapted ESMO Clinical Practice Guidelines for the management of patients with locally-advanced unresectable non-small-cell lung cancer: a KSMO-ESMO initiative endorsed by CSCO, ISMPO, JSMO, MOS, SSO and TOS

Published Date: Feb-2020

Name of Journal, Conference Books or Other Publications: Annals of Oncology

Publication DOI: doi: 10.1016/j.annonc.2019.10.026

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Park K, Vansteenkiste J, Lee KH, Pentheroudakis G, Zhou C, Prabhash K, Seto T, Voon PJ, Tan DSW, Yang JCH, Wang J, Babu KG, Nakayama Y, Alip A, Chua KLM, Cheng JC, Senan S, Ahn YC, Kim TY, Ahn HK, Peters S, Yoshino T, Douillard JY

Link to article in Journal: https://www.annalsofoncology.org/article/S0923-7534(19)36083-1/fulltext

Asian Thoracic Oncology Research Group Expert Consensus Statement on Optimal Management of Stage III NSCLC

Published Date: Mar-2020

Name of Journal, Conference Books or Other Publications: Journal of Thoracic Oncology

Publication DOI: doi: 10.1016/j.jtho.2019.10.022

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Wan Ling Tan, Kevin L.M. Chua, Chia-Chi Lin, Victor H.F. Lee, Lye Mun Tho, Anthony W. Chan, Gwo Fuang Ho, Thanyanan Reungwetwattana, James C. Yang, Dong-Wan Kim, Ross A. Soo, Yong Chan Ahn, Hiroshi Onishi, Myung-Ju Ahn, Tony S.K. Mok, Daniel S.W. Tan, Fan Yang

Link to article in Journal: https://www.jto.org/article/S1556-0864(19)33640-8/fulltext

Pan-Asian adapted Clinical Practice Guidelines for the management of patients with metastatic non-small-cell lung cancer: a CSCO-ESMO initiative endorsed by JSMO, KSMO, MOS, SSO and TOS

Published Date: Feb-2019

Name of Journal, Conference Books or Other Publications: Annals of Oncology

Publication DOI: doi: 10.1093/annonc/mdy554

Name of All Authors/Co-Authors and Institutions according to authorship order as published: Y.-L. Wu, D. Planchard, S. Lu, H. Sun, N. Yamamoto, D.-W. Kim, D.S.W. Tan, J.C.-H. Yang, M. Azrif, T. Mitsudomi, K. Park, R.A. Soo, J.W.C. Chang, A. Alip, S. Peters, J.-Y. Douillard

Link to article in Journal: https://www.annalsofoncology.org/article/S0923-7534(19)31046-4/fulltext

Recommendations to improve the clinical adoption of NGS-based cancer diagnostics in Singapore

Published Date: Aug-2020

Name of Journal, Conference Books or Other Publications: Asia Pacific Journal of Clinical Oncology

Publication DOI: doi: 10.1111/ajco.13339

Name of All Authors/Co-Authors and Institutions according to authorship order as published: David Shao-Peng Tan,Daniel Shao-Weng Tan,Iain Bee Huat Tan,Benedict Yan,Su Pin Choo,Wee Joo Chng,William Ying Khee Hwang

Link to article in Journal: https://onlinelibrary.wiley.com/doi/10.1111/ajco.13339